BPA (Bisphenol A)
Also: Bisphenol A · 4,4'-isopropylidenediphenol · 2,2-bis(4-hydroxyphenyl)propane · resin code 7
Avoid — a well-documented endocrine disruptor associated in women with lower egg quality, reduced fertilization and implantation, and PCOS.
Fertility & hormonal impact
BPA binds estrogen receptors (ERα and ERβ) and interferes with steroidogenesis. In women, higher urinary or serum BPA has been associated with altered estradiol and gonadotropin levels, lower oocyte (egg) quality, reduced fertilization rates, and impaired implantation in IVF cohorts. Elevated BPA is repeatedly observed in women with polycystic ovary syndrome (PCOS) and has been linked in some studies to recurrent miscarriage. BPA appears to act directly on the ovary, disrupting follicle maturation and meiotic spindle formation in maturing oocytes. It also interferes with thyroid-hormone signaling, which is important for normal ovulation and early pregnancy.
Found in.
Two jurisdictions, two different verdicts.
Banned in baby bottles since 2011. Migration limit reduced to 0.05 mg/kg under EU Regulation 2018/213. Classified as a Substance of Very High Concern (SVHC) under REACH.
Banned in baby bottles and sippy cups (2012). Authorized for other food contact uses. FDA position: safe at current exposure levels, though this is contested by independent researchers.
The receipts.
- [01]Liu et al. 2015 — BPA exposure and reproductive hormones (PubMed)pubmed.ncbi.nlm.nih.gov/25818109/
- [02]Meeker et al. 2010 — Urinary BPA and reproductive endpoints (PubMed)pubmed.ncbi.nlm.nih.gov/20656017/
- [03]EU Regulation 2018/213 — BPA migration limitseur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32018R0213
Find BPA (Bisphenol A) before it finds you.
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